Oral antibiotics are best used with topical retinoids and benzoyl peroxide. Studies have found that using topical benzoyl peroxide along with oral antibiotics may reduce the risk of developing antibiotic resistance. Antibiotics may cause side effects, such as an upset stomach and dizziness. These drugs also increase your skin's sun sensitivity. You can reduce the amount of time you need to take an antibiotic by using all of the medicine in your treatment plan and gentle skin care. Acne isn’t an infection, but an antibiotic can provide real relief from deep, painful breakouts. Certain antibiotics like doxycycline (dox-ē-cyc-lean) and. Acne Aid Clean Facial Antibiotics For Acne Side Effects Detoxification Foam is a deep Facial Acne Vulgariscleaning system for oily skin. The facial foam is effective for greasy and acne prone skin without drying the skin.